Drug Delivery Vehicles
A drug carrier enhances the selectivity, effectiveness and safety of drug administration. Drug carriers are mainly used to control the release of a drug into systemic circulation. This can be accomplished either by slow release of the drug over a long period of time (typically diffusion) or by triggering the release at the target by stimulus, which include pH changes, application of heat and activation by light. Drug carriers improve the bioavailability of poorly water soluble drugs or membrane permeable drugs.
An ideal drug delivery vehicle must be non-toxic, non-immunogenic, biocompatible and biodegradable Different methods of drug attachment to the carriers include adsorption, integration, encapsulation, and covalent bonding.